casno. : 2381089-83-2
Name | Retatrutide |
CAS NO | 2381089-83-2 |
Molecular Formula | C221H342N46O68 |
IC50 & Target | EC50 (for human): 5.79 (GCGR), 0.0643 (GIPR), 0.775 nM (GLP-1R) |
EC50 (for mouse) | 2.32 (GCGR), 0.191 (GIPR), 0.794 nM (GLP-1R) |
Ki (for human | 5.6 (GCGR), 0.057 (GIPR), 7.2 nM (GLP-1R) |
Ki (for mouse) | 73 (GCGR), 2.8 (GIPR), 1.3 nM (GLP-1R) |
Product Introduction | Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity. |
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